The BDNF gene, member of the neurotrophin family, encodes a protein called brain-derived neurotrophic factor which includes NGF, NT-3, and NT-4/5. It is a neurotrophin, or nerve growth factor, that promotes the survival of existing neurons and the formation of new neurons from neural stem cells. The BDNF gene has eight different promoters and eight possible transcripts.
EpigenDx offers BDNF gene methylation assays and analysis services, which cover a total of ten gene regions within BDNF and 101 CpG sites.