EpigenDx brings extensive experience in the field of genetic and epigenetic clinical research, delivering quality products and laboratory services with a sharp focus on DNA methylation analysis, gene expression profiling, and mutation analysis. Achieve superior enrichment efficiency with EpigenDx solutions.
DNA Methylation Solutions
Applications
Clinical Trials
Clinical trial sample management is a service that EpigenDx provides to the nation’s top academic, pharmaceutical and biotechnology researchers. By providing integrity and regulatory compliance, we ensure all aspects for FDA approval are set forth no matter what phase of the clinical trial a drug is in.
Sample Preparation
Samples must be appropriately processed and prepared before they can be evaluated utilizing advanced scientific equipment and instruments. Our various options of clinical and discovery bioprocessing services ensure that the value of your samples is maintained throughout their life span.
Biomarker Discovery and Validation
EpigenDx provides custom genetic and epigenetic laboratory services to global leaders ranging from academic, pharmaceutical and biotechnology institutions. Biomarkers have various applications including disease detection, diagnosis, prognosis, prediction of response to intervention and disease monitoring. Protein biomarkers can be analyzed using a wide range of instrumentation and can be quantified from complex biological samples.
Method Development and Assay Validation
EpigenDx has expertise in PCR and assay design, and we validate the assay conditions using quantitative Pyrosequencing methylation technology to ensure methylated and unmethylated DNA are amplified at the same efficiency. We provide complete primer sets and assay conditions to our customers, optimized for bisulfite sequencing and other DNA methylation applications such as COBRA and HRM real-time PCR.
15,000+ Off-the-Shelf Validated DNA Methylation Assays
Human, Mouse, Rat, Monkey, and more.
Research Area
Cancer Research
To assess cancer-associated mutations and other biomarkers, cancer researchers can utilize whole genome, exome, and targeted amplicon next generation sequencing methods.
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Immunology & Infectious Disease
Next-generation sequencing is used by infectious disease researchers to find new viruses, monitor host-pathogen interactions, analyze pathogen evolution, and anticipate where drug-resistant genotypes may emerge.
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Neuroscience
Next-generation sequencing technologies have resulted in remarkable increases in our understanding of human neurological disorders through the identification of disease-causing or protective sequence variants.
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Drug Development Research
Diverse NGS methods such as targeted next-gen sequencing, pyrosequencing or transcriptome sequencing can be used to perform molecular profiling, and to discover novel drug biomarkers or targets.
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Applied Industries
Academic Research
Clinical Research
Hospitals & Clinics
Pharma & Biotech
NGS Test Menu
HUMAN
NGS162 – Human ANO1
(anoctamin 1)
NGS158 – Human ST3GAL4
(ST3 beta-galactoside alpha-2,3-sialyltransferase 4)
NGS153 – Human FUT7
(fucosyltransferase 7)
NGS151 – Human CEBPA
(CCAAT enhancer binding protein alpha)
NGS149 – Human MAD1L1
(mitotic arrest deficient 1 like 1)
NGS148 – Human CDKN1A
(cyclin dependent kinase inhibitor 1A)
NGS142 – Human EPHA2
(ephrin type-A receptor 2)
NGS133 – Human OTX2
(orthodenticle homeobox 2)
NGS123 – Human PMAIP1
(phorbol-12-myristate-13-acetate-induced protein 1)
NGS104/087 – Human SRD5A1 & SRD5A2
(steroid 5 alpha-reductase 1 & 2)
NGS100 – Human TP73
(tumor protein p73)
NGS092 – Human ID3
(inhibitor of DNA binding 3)
NGS088 – Human OTC & CPS1
(Urea Cycle)
NGS070V3 – Human FOXP3
(forkhead box P3) Regulators
NGS006V1 – Human RUNX3
(Runt-related transcription factor 3)
MOUSE
NGS161 – Mouse Evl
(Ena-vasodilator stimulated phosphoprotein)
NGS159 – Mouse Arc
(activity regulated cytoskeletal-associated protein)
NGS156 – Mouse Jarid2
(jumonji, AT rich interactive domain 2)
NGS154 – Mouse Pdgfb
(platelet derived growth factor) & Mapk1 (mitogen-activated protein kinase 1)
NGS150V1 – Mouse Elovl2
(elongation of very long chain fatty acids 2)
NGS146 – Mouse CNS
(central nervous system)
NGS096/095 – Mouse Rxra & Vdr
(retinoid X receptor alpha & vitamin D receptor)
RAT
NGS160 – Rat Pick1
(protein interacting with PRKCA 1)
NGS152 – Rat Fkbp5
(FKBP prolyl isomerase 5)
MONKEY
Not Seeing What You’re Looking For?
We’d be more than happy to assist you. EpigenDx provides custom assay design and analytical services with an assay database of thousands of Off-the-Shelf designs ready to go. Not only do we provide aggressive timelines with regular project updates, you will also get the highest quality technical support and consultation from design phase through project completion and data delivery.
EpigenDx
Experts in DNA Methylation
Now Offering GLP and GCP Compliant Laboratory Services
LEARN MOREEpigenDx Offers Many Customized Services
